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Of Inflammasomes and Alarmins: IL-1β and IL-1α in Kidney Disease

Kidney injury implies danger signaling and a response by the immune system. The inflammasome is a central danger recognition platform that triggers local and systemic inflammation. In immune cells, inflammasome activation causes the release of mature IL-1β and of the alarmin IL-1α. Dying cells relea...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autor principal: Anders, Hans-Joachim
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004665/
https://ncbi.nlm.nih.gov/pubmed/27516236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020177
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