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Of Inflammasomes and Alarmins: IL-1β and IL-1α in Kidney Disease
Kidney injury implies danger signaling and a response by the immune system. The inflammasome is a central danger recognition platform that triggers local and systemic inflammation. In immune cells, inflammasome activation causes the release of mature IL-1β and of the alarmin IL-1α. Dying cells relea...
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| Published in: | J Am Soc Nephrol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Nephrology
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004665/ https://ncbi.nlm.nih.gov/pubmed/27516236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016020177 |
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