Far Upstream Element-Binding Protein 1 Binds the 3′ Untranslated Region of PKD2 and Suppresses Its Translation

Autosomal dominant polycystic kidney disease pathogenesis can be recapitulated in animal models by gene mutations in or dosage alterations of polycystic kidney disease 1 (PKD1) or PKD2, demonstrating that too much and too little PKD1/PKD2 are both pathogenic. Gene dosage manipulation has become an a...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Zheng, Wang, Shen, Fan, Hu, Ruikun, Roy, Birbickram, Yang, JungWoo, Wang, Qian, Zhang, Fan, King, Jennifer C., Sergi, Consolato, Liu, Song-Mei, Cordat, Emmanuelle, Tang, Jingfeng, Cao, Ying, Ali, Declan, Chen, Xing-Zhen
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2016
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004656/
https://ncbi.nlm.nih.gov/pubmed/26839368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015070836
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