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Far Upstream Element-Binding Protein 1 Binds the 3′ Untranslated Region of PKD2 and Suppresses Its Translation

Autosomal dominant polycystic kidney disease pathogenesis can be recapitulated in animal models by gene mutations in or dosage alterations of polycystic kidney disease 1 (PKD1) or PKD2, demonstrating that too much and too little PKD1/PKD2 are both pathogenic. Gene dosage manipulation has become an a...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Zheng, Wang, Shen, Fan, Hu, Ruikun, Roy, Birbickram, Yang, JungWoo, Wang, Qian, Zhang, Fan, King, Jennifer C., Sergi, Consolato, Liu, Song-Mei, Cordat, Emmanuelle, Tang, Jingfeng, Cao, Ying, Ali, Declan, Chen, Xing-Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004656/
https://ncbi.nlm.nih.gov/pubmed/26839368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015070836
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