Far Upstream Element-Binding Protein 1 Binds the 3′ Untranslated Region of PKD2 and Suppresses Its Translation

Autosomal dominant polycystic kidney disease pathogenesis can be recapitulated in animal models by gene mutations in or dosage alterations of polycystic kidney disease 1 (PKD1) or PKD2, demonstrating that too much and too little PKD1/PKD2 are both pathogenic. Gene dosage manipulation has become an a...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Main Authors: Zheng, Wang, Shen, Fan, Hu, Ruikun, Roy, Birbickram, Yang, JungWoo, Wang, Qian, Zhang, Fan, King, Jennifer C., Sergi, Consolato, Liu, Song-Mei, Cordat, Emmanuelle, Tang, Jingfeng, Cao, Ying, Ali, Declan, Chen, Xing-Zhen
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2016
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004656/
https://ncbi.nlm.nih.gov/pubmed/26839368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015070836
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