Rare Variants in the Complement Factor H–Related Protein 5 Gene Contribute to Genetic Susceptibility to IgA Nephropathy

A recent genome–wide association study of IgA nephropathy (IgAN) identified 1q32, which contains multiple complement regulatory genes, including the complement factor H (CFH) gene and the complement factor H–related (CFHRs) genes, as an IgAN susceptibility locus. Abnormal complement activation cause...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Zhai, Ya-Ling, Meng, Si-Jun, Zhu, Li, Shi, Su-Fang, Wang, Su-Xia, Liu, Li-Jun, Lv, Ji-Cheng, Yu, Feng, Zhao, Ming-Hui, Zhang, Hong
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2016
Subjects:
Clinical Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004636/
https://ncbi.nlm.nih.gov/pubmed/26825529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015010012
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