A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit

PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using phosphoproteomics combined with kinetic modeling to extract B55-dependent rate...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Cundell, Michael J., Hutter, Lukas H., Nunes Bastos, Ricardo, Poser, Elena, Holder, James, Mohammed, Shabaz, Novak, Bela, Barr, Francis A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004449/
https://ncbi.nlm.nih.gov/pubmed/27551054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606033
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