A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit

PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using phosphoproteomics combined with kinetic modeling to extract B55-dependent rate...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Cundell, Michael J., Hutter, Lukas H., Nunes Bastos, Ricardo, Poser, Elena, Holder, James, Mohammed, Shabaz, Novak, Bela, Barr, Francis A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004449/
https://ncbi.nlm.nih.gov/pubmed/27551054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606033
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