A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit

PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using phosphoproteomics combined with kinetic modeling to extract B55-dependent rate...

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Publicat a:J Cell Biol
Autors principals: Cundell, Michael J., Hutter, Lukas H., Nunes Bastos, Ricardo, Poser, Elena, Holder, James, Mohammed, Shabaz, Novak, Bela, Barr, Francis A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004449/
https://ncbi.nlm.nih.gov/pubmed/27551054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201606033
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