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Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion

Macropinocytosis, the internalization of extracellular fluid and material by plasma membrane ruffles, is critical for antigen presentation, cell metabolism, and signaling. Macropinosomes mature through homotypic and heterotypic fusion with endosomes and ultimately merge with lysosomes. The molecular...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Cell Biol
Päätekijät: Dolat, Lee, Spiliotis, Elias T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004444/
https://ncbi.nlm.nih.gov/pubmed/27551056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603030
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