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Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2(−/−)γc(−/−) mice

Juvenile myelomonocytic leukemia is a clonal malignant disease affecting young children. Current cure rates, even with allogeneic hematopoietic stem cell transplantation, are no better than 50%–60%. Pre-clinical research on juvenile myelomonocytic leukemia is urgently needed for the identification o...

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Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Krombholz, Christopher Felix, Aumann, Konrad, Kollek, Matthias, Bertele, Daniela, Fluhr, Silvia, Kunze, Mirjam, Niemeyer, Charlotte M., Flotho, Christian, Erlacher, Miriam
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004370/
https://ncbi.nlm.nih.gov/pubmed/26888021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.138545
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