An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation

BACKGROUND: Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic psychosis and altered cognitive function. Despite success in identifying genetic variants associated with schizophrenia, there remains uncertainty about the causal genes involved in disease pathogene...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Hannon, Eilis, Dempster, Emma, Viana, Joana, Burrage, Joe, Smith, Adam R., Macdonald, Ruby, St Clair, David, Mustard, Colette, Breen, Gerome, Therman, Sebastian, Kaprio, Jaakko, Toulopoulou, Timothea, Pol, Hilleke E. Hulshoff, Bohlken, Marc M., Kahn, Rene S., Nenadic, Igor, Hultman, Christina M., Murray, Robin M., Collier, David A., Bass, Nick, Gurling, Hugh, McQuillin, Andrew, Schalkwyk, Leonard, Mill, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004279/
https://ncbi.nlm.nih.gov/pubmed/27572077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1041-x
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