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Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo

Natural forms of prion diseases frequently originate by oral (p.o.) infection. However, quantitative information on the gastro-intestinal (GI) absorption of prions (i.e. the bioavailability and subsequent biodistribution) is mostly unknown. The main goal of this study was to evaluate the fate of pri...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Urayama, Akihiko, Concha-Marambio, Luis, Khan, Uffaf, Bravo-Alegria, Javiera, Kharat, Vineetkumar, Soto, Claudio
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004172/
https://ncbi.nlm.nih.gov/pubmed/27573341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32338
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