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Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo

Natural forms of prion diseases frequently originate by oral (p.o.) infection. However, quantitative information on the gastro-intestinal (GI) absorption of prions (i.e. the bioavailability and subsequent biodistribution) is mostly unknown. The main goal of this study was to evaluate the fate of pri...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Urayama, Akihiko, Concha-Marambio, Luis, Khan, Uffaf, Bravo-Alegria, Javiera, Kharat, Vineetkumar, Soto, Claudio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004172/
https://ncbi.nlm.nih.gov/pubmed/27573341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32338
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