EF24 inhibits tumor growth and metastasis via suppressing NF-kappaB dependent pathways in human cholangiocarcinoma

A synthetic monoketone analog of curcumin, termed 3, 5-bis (2-flurobenzylidene) piperidin-4-one (EF24), has been reported to inhibit the growth of a variety of cancer cells both in vitro and in vivo. However, whether EF24 has anticancer effects on cholangiocarcinoma (CCA) cells and the mechanisms re...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yin, Da-long, Liang, Ying-jian, Zheng, Tong-sen, Song, Rui-peng, Wang, Jia-bei, Sun, Bo-shi, Pan, Shang-ha, Qu, Lian-dong, Liu, Jia-ren, Jiang, Hong-chi, Liu, Lian-xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004153/
https://ncbi.nlm.nih.gov/pubmed/27571770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32167
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