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Protective role of Smad6 in inflammation-induced valvular cell calcification

Calcific aortic vascular and valvular disease (CAVD) is associated with hyperlipidemia, the effects of which occur through chronic inflammation. Evidence suggests that inhibitory small mothers against decapentaplegic (I-Smads; Smad6 and 7) regulate valve embryogenesis and may serve as a mitigating f...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Li, Xin, Lim, Jina J., Lu, Jinxiu, Pedego, Taylor M., Demer, Linda, Tintut, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003537/
https://ncbi.nlm.nih.gov/pubmed/25864564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25186
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