Histone arginine methylation in cocaine action in the nucleus accumbens

Repeated cocaine exposure regulates transcriptional regulation within the nucleus accumbens (NAc), and epigenetic mechanisms—such as histone acetylation and methylation on Lys residues—have been linked to these lasting actions of cocaine. In contrast to Lys methylation, the role of histone Arg (R) m...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Damez-Werno, Diane M., Sun, HaoSheng, Scobie, Kimberly N., Shao, Ningyi, Rabkin, Jaclyn, Dias, Caroline, Calipari, Erin S., Maze, Ian, Pena, Catherine J., Walker, Deena M., Cahill, Michael E., Chandra, Ramesh, Gancarz, Amy, Mouzon, Ezekiell, Landry, Joseph A., Cates, Hannah, Lobo, Mary-Kay, Dietz, David, Allis, C. David, Guccione, Ernesto, Turecki, Gustavo, Defilippi, Paola, Neve, Rachael L., Hurd, Yasmin L., Shen, Li, Nestler, Eric J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003250/
https://ncbi.nlm.nih.gov/pubmed/27506785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605045113
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