Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease

Hydroxyurea (HU) has been used clinically to reduce the frequency of painful crisis and the need for blood transfusion in sickle cell disease (SCD) patients. However, the mechanisms underlying such beneficial effects of HU treatment are still not fully understood. Studies have indicated a weak corre...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hosseini, Poorya, Abidi, Sabia Z., Du, E, Papageorgiou, Dimitrios P., Choi, Youngwoon, Park, YongKeun, Higgins, John M., Kato, Gregory J., Suresh, Subra, Dao, Ming, Yaqoob, Zahid, So, Peter T. C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003247/
https://ncbi.nlm.nih.gov/pubmed/27512047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610435113
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