Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution

Antigen processing and presentation genes found within the MHC are among the most highly polymorphic genes of vertebrate genomes, providing populations with diverse immune responses to a wide array of pathogens. Here, we describe transcriptome, exome, and whole-genome sequencing of clonal zebrafish,...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: McConnell, Sean C., Hernandez, Kyle M., Wcisel, Dustin J., Kettleborough, Ross N., Stemple, Derek L., Yoder, Jeffrey A., Andrade, Jorge, de Jong, Jill L. O.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003237/
https://ncbi.nlm.nih.gov/pubmed/27493218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607602113
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