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Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution

Antigen processing and presentation genes found within the MHC are among the most highly polymorphic genes of vertebrate genomes, providing populations with diverse immune responses to a wide array of pathogens. Here, we describe transcriptome, exome, and whole-genome sequencing of clonal zebrafish,...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: McConnell, Sean C., Hernandez, Kyle M., Wcisel, Dustin J., Kettleborough, Ross N., Stemple, Derek L., Yoder, Jeffrey A., Andrade, Jorge, de Jong, Jill L. O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003237/
https://ncbi.nlm.nih.gov/pubmed/27493218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607602113
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