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Association between Functional Small Airway Disease and FEV(1) Decline in Chronic Obstructive Pulmonary Disease

Rationale: The small conducting airways are the major site of airflow obstruction in chronic obstructive pulmonary disease and may precede emphysema development. Objectives: We hypothesized a novel computed tomography (CT) biomarker of small airway disease predicts FEV(1) decline. Methods: We analyz...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Bhatt, Surya P., Soler, Xavier, Wang, Xin, Murray, Susan, Anzueto, Antonio R., Beaty, Terri H., Boriek, Aladin M., Casaburi, Richard, Criner, Gerard J., Diaz, Alejandro A., Dransfield, Mark T., Curran-Everett, Douglas, Galbán, Craig J., Hoffman, Eric A., Hogg, James C., Kazerooni, Ella A., Kim, Victor, Kinney, Gregory L., Lagstein, Amir, Lynch, David A., Make, Barry J., Martinez, Fernando J., Ramsdell, Joe W., Reddy, Rishindra, Ross, Brian D., Rossiter, Harry B., Steiner, Robert M., Strand, Matthew J., van Beek, Edwin J. R., Wan, Emily S., Washko, George R., Wells, J. Michael, Wendt, Chris H., Wise, Robert A., Silverman, Edwin K., Crapo, James D., Bowler, Russell P., Han, MeiLan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003216/
https://ncbi.nlm.nih.gov/pubmed/26808615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201511-2219OC
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