Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes

LPL hydrolyzes triglycerides in triglyceride-rich lipoproteins along the capillaries of heart, skeletal muscle, and adipose tissue. The activity of LPL is repressed by angiopoietin-like 4 (ANGPTL4) but the underlying mechanisms have not been fully elucidated. Our objective was to study the cellular...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Dijk, Wieneke, Beigneux, Anne P., Larsson, Mikael, Bensadoun, André, Young, Stephen G., Kersten, Sander
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003152/
https://ncbi.nlm.nih.gov/pubmed/27034464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M067363
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