Structure and function of the bacterial decapping enzyme NudC

RNA capping and decapping are thought to be distinctive features of eukaryotes. Recently, the redox cofactor NAD was discovered to be attached to small regulatory RNAs in bacteria in a cap-like manner, and Nudix hydrolase NudC was found to act as a NAD decapping enzyme in vitro and in vivo. Here, cr...

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Bibliographic Details
Published in:Nat Chem Biol
Main Authors: Höfer, Katharina, Li, Sisi, Abele, Florian, Frindert, Jens, Schlotthauer, Jasmin, Grawenhoff, Julia, Du, Jiamu, Patel, Dinshaw J., Jäschke, Andres
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003112/
https://ncbi.nlm.nih.gov/pubmed/27428510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2132
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