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Structure and function of the bacterial decapping enzyme NudC

RNA capping and decapping are thought to be distinctive features of eukaryotes. Recently, the redox cofactor NAD was discovered to be attached to small regulatory RNAs in bacteria in a cap-like manner, and Nudix hydrolase NudC was found to act as a NAD decapping enzyme in vitro and in vivo. Here, cr...

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Bibliografiske detaljer
Udgivet i:Nat Chem Biol
Main Authors: Höfer, Katharina, Li, Sisi, Abele, Florian, Frindert, Jens, Schlotthauer, Jasmin, Grawenhoff, Julia, Du, Jiamu, Patel, Dinshaw J., Jäschke, Andres
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003112/
https://ncbi.nlm.nih.gov/pubmed/27428510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2132
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