Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia

Numerous clinical trials are utilizing mesenchymal stem cells (MSC) to treat critical limb ischemia, primarily for their ability to secrete signals that promote revascularization. These cells have demonstrated clinical safety, but their efficacy has been limited, possibly because these paracrine sig...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther Methods Clin Dev
Auteurs principaux: Beegle, Julie R, Magner, Nataly Lessa, Kalomoiris, Stefanos, Harding, Aja, Zhou, Ping, Nacey, Catherine, White, Jeannine Logan, Pepper, Karen, Gruenloh, William, Annett, Geralyn, Nolta, Jan A, Fierro, Fernando A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003097/
https://ncbi.nlm.nih.gov/pubmed/27610394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.53
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