Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia

Numerous clinical trials are utilizing mesenchymal stem cells (MSC) to treat critical limb ischemia, primarily for their ability to secrete signals that promote revascularization. These cells have demonstrated clinical safety, but their efficacy has been limited, possibly because these paracrine sig...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther Methods Clin Dev
Prif Awduron: Beegle, Julie R, Magner, Nataly Lessa, Kalomoiris, Stefanos, Harding, Aja, Zhou, Ping, Nacey, Catherine, White, Jeannine Logan, Pepper, Karen, Gruenloh, William, Annett, Geralyn, Nolta, Jan A, Fierro, Fernando A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003097/
https://ncbi.nlm.nih.gov/pubmed/27610394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.53
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