Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia

Numerous clinical trials are utilizing mesenchymal stem cells (MSC) to treat critical limb ischemia, primarily for their ability to secrete signals that promote revascularization. These cells have demonstrated clinical safety, but their efficacy has been limited, possibly because these paracrine sig...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Beegle, Julie R, Magner, Nataly Lessa, Kalomoiris, Stefanos, Harding, Aja, Zhou, Ping, Nacey, Catherine, White, Jeannine Logan, Pepper, Karen, Gruenloh, William, Annett, Geralyn, Nolta, Jan A, Fierro, Fernando A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003097/
https://ncbi.nlm.nih.gov/pubmed/27610394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.53
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