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Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome

Silencing the gene FMR1 in fragile X syndrome (FXS) with consequent loss of its protein product, FMRP, results in intellectual disability, hyperactivity, anxiety, seizure disorders, and autism-like behavior. In a mouse model (Fmr1 knockout (KO)) of FXS, a deficit in performance on the passive avoida...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Qin, Mei, Zeidler, Zachary, Moulton, Kristen, Krych, Leland, Xia, Zengyan, Smith, Carolyn B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003021/
https://ncbi.nlm.nih.gov/pubmed/25979787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2015.05.003
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