Cerebral Protein Synthesis in a Knockin Mouse Model of the Fragile X Premutation

The (CGG)n-repeat in the 5′-untranslated region of the fragile X mental retardation gene (FMR1) gene is polymorphic and may become unstable on transmission to the next generation. In fragile X syndrome, CGG repeat lengths exceed 200, resulting in silencing of FMR1 and absence of its protein product,...

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Detalhes bibliográficos
Main Authors: Qin, Mei, Huang, Tianjian, Liu, Zhonghua, Kader, Michael, Burlin, Thomas, Xia, Zengyan, Zeidler, Zachary, Hukema, Renate K., Smith, Carolyn B.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187003/
https://ncbi.nlm.nih.gov/pubmed/25290064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091414551957
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