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Free Energy Landscape of Lipid Interactions with Regulatory Binding Sites on the Transmembrane Domain of the EGF Receptor

[Image: see text] Lipid molecules can bind to specific sites on integral membrane proteins, modulating their structure and function. We have undertaken coarse-grained simulations to calculate free energy profiles for glycolipids and phospholipids interacting with modulatory sites on the transmembran...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Hedger, George, Shorthouse, David, Koldsø, Heidi, Sansom, Mark S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002933/
https://ncbi.nlm.nih.gov/pubmed/27109430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b01387
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