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The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids
Receptor tyrosine kinases (RTKs) play a critical role in diverse cellular processes and their activity is regulated by lipids in the surrounding membrane, including PIP(2) (phosphatidylinositol-4,5-bisphosphate) in the inner leaflet, and GM3 (monosialodihexosylganglioside) in the outer leaflet. Howe...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361843/ https://ncbi.nlm.nih.gov/pubmed/25779975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09198 |
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