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Dependence of RIG-I Nucleic Acid-Binding and ATP Hydrolysis on Activation of Type I Interferon Response

Exogenous nucleic acids induce an innate immune response in mammalian host cells through activation of the retinoic acid-inducible gene I (RIG-I). We evaluated RIG-I protein for RNA binding and ATPase stimulation with RNA ligands to investigate the correlation with the extent of immune response thro...

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Detalhes bibliográficos
Publicado no:Immune Netw
Main Authors: Baek, Yu Mi, Yoon, Soojin, Hwang, Yeo Eun, Kim, Dong-Eun
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002451/
https://ncbi.nlm.nih.gov/pubmed/27574504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2016.16.4.249
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