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Regulation of sclerostin expression in multiple myeloma by Dkk-1; a potential therapeutic strategy for myeloma bone disease

Sclerostin is a potent inhibitor of osteoblastogenesis. Interestingly, newly diagnosed multiple myeloma (MM) patients have high levels of circulating sclerostin that correlate with disease stage and fractures. However, the source and impact of sclerostin in MM remains to be defined. Our goal was to...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Eda, Homare, Santo, Loredana, Wein, Marc N., Hu, Dorothy Z., Cirstea, Diana D., Nemani, Neeharika, Tai, Yu-Tzu, Raines, Sarah E., Kuhstoss, Stuart Allen, Munshi, Nikhil C., Kronenberg, Henry M., Raje, Noopur S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002355/
https://ncbi.nlm.nih.gov/pubmed/26763740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2789
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