Siponimod (BAF312) prevents synaptic neurodegeneration in experimental multiple sclerosis

BACKGROUND: Data from multiple sclerosis (MS) and the MS rodent model, experimental autoimmune encephalomyelitis (EAE), highlighted an inflammation-dependent synaptopathy at the basis of the neurodegenerative damage causing irreversible disability in these disorders. This synaptopathy is characteriz...

Full description

Saved in:
Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Gentile, Antonietta, Musella, Alessandra, Bullitta, Silvia, Fresegna, Diego, De Vito, Francesca, Fantozzi, Roberta, Piras, Eleonora, Gargano, Francesca, Borsellino, Giovanna, Battistini, Luca, Schubart, Anna, Mandolesi, Georgia, Centonze, Diego
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002118/
https://ncbi.nlm.nih.gov/pubmed/27566665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0686-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items