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Solvation Thermodynamics of Oligoglycine with Respect to Chain Length and Flexibility

Oligoglycine is a backbone mimic for all proteins and is prevalent in the sequences of intrinsically disordered proteins. We have computed the absolute chemical potential of glycine oligomers at infinite dilution by simulation with the CHARMM36 and Amber ff12SB force fields. We performed a thermodyn...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Drake, Justin A., Harris, Robert C., Pettitt, B. Montgomery
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002085/
https://ncbi.nlm.nih.gov/pubmed/27558719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.07.013
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