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Solvation Thermodynamics of Oligoglycine with Respect to Chain Length and Flexibility

Oligoglycine is a backbone mimic for all proteins and is prevalent in the sequences of intrinsically disordered proteins. We have computed the absolute chemical potential of glycine oligomers at infinite dilution by simulation with the CHARMM36 and Amber ff12SB force fields. We performed a thermodyn...

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Bibliographic Details
Published in:Biophys J
Main Authors: Drake, Justin A., Harris, Robert C., Pettitt, B. Montgomery
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002085/
https://ncbi.nlm.nih.gov/pubmed/27558719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.07.013
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