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Do the Apoe−/− and Ldlr−/−mice yield the same insight on atherogenesis?

Murine models of atherosclerosis are useful for investigating the environmental and genetic influences on lesion formation and composition. Apoe−/− and Ldlr−/− are the two models most extensively used models. The models differ in important ways with respect to the precise mechanism by which their ab...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Getz, Godfrey S., Reardon, Catherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001905/
https://ncbi.nlm.nih.gov/pubmed/27386935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.306874
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