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ApoE knockout and knockin mice: the history of their contribution to the understanding of atherogenesis

ApoE is a multifunctional protein that is expressed by many cell types that influences many aspects of cardiovascular physiology. In humans, there are three major allelic variants that differentially influence lipoprotein metabolism and risk for the development of atherosclerosis. Apoe-deficient mic...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Getz, Godfrey S., Reardon, Catherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847636/
https://ncbi.nlm.nih.gov/pubmed/27015743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R067249
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