Monocyte microRNA expression in active systemic juvenile idiopathic arthritis implicates miR-125a-5p in polarized monocyte phenotypes

OBJECTIVE: Systemic juvenile idiopathic arthritis (SJIA) is an inflammatory disease of childhood, in which cells of the monomyelocytoid lineage are felt to be key effector cells. Monocytes from SJIA patients have a distinct phenotype, with features of both M1 well as M2 alternative activation. Micro...

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Veröffentlicht in:Arthritis Rheumatol
Hauptverfasser: Schulert, Grant S., Fall, Ndate, Harley, John B., Shen, Nan, Lovell, Daniel J., Thornton, Sherry, Grom, Alexei A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001902/
https://ncbi.nlm.nih.gov/pubmed/27014994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39694
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