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The Limited Role of Interferon-γ in Systemic Juvenile Idiopathic Arthritis Cannot Be Explained by Cellular Hyporesponsiveness

OBJECTIVE: Systemic juvenile idiopathic arthritis (SJIA) is an autoinflammatory syndrome where the myelomonocytic lineage is believed to play a pivotal role in pathogenesis. Traditionally, inflammatory macrophages are driven by interferon-γ (IFN-γ), yet recent gene expression studies of peripheral b...

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Detalhes bibliográficos
Main Authors: Sikora, Keith A., Fall, Ndate, Thornton, Sherry, Grom, Alexei A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482423/
https://ncbi.nlm.nih.gov/pubmed/22740319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34604
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