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Inhibiting GPIbα shedding preserves post-transfusion recovery and hemostatic function of platelets after prolonged storage
OBJECTIVES: The platelet storage lesion accelerates platelet clearance after transfusion, but the underlying molecular mechanism remains elusive. Although inhibiting sheddase activity hampers clearance of platelets with storage lesion, the target platelet protein responsible for ectodomain shedding-...
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| Publicat a: | Arterioscler Thromb Vasc Biol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001887/ https://ncbi.nlm.nih.gov/pubmed/27417583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307639 |
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