Repulsive DNA-DNA interactions accelerate viral DNA packaging in phage phi29

We use optical tweezers to study the effect of attractive versus repulsive DNA-DNA interactions on motor-driven viral packaging. Screening of repulsive interactions accelerates packaging, but induction of attractive interactions by spermidine(3+) causes heterogeneous dynamics. Acceleration is observ...

Full description

Saved in:
Bibliographic Details
Published in:Phys Rev Lett
Main Authors: Keller, Nicholas, delToro, Damian, Grimes, Shelley, Jardine, Paul J., Smith, Douglas E.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001848/
https://ncbi.nlm.nih.gov/pubmed/24996111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevLett.112.248101
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items