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Osthole activates glucose uptake but blocks full activation in L929 fibroblast cells, and inhibits uptake in HCLE cells

AIMS: Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines that exclusively express GLUT1. MAIN METH...

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Podrobná bibliografie
Vydáno v:Life Sci
Hlavní autoři: Alabi, Ola D., Gunnink, Stephen M., Kuiper, Benjamin D., Kerk, Samuel A., Braun, Emily, Louters, Larry L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001691/
https://ncbi.nlm.nih.gov/pubmed/24657891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2014.03.017
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