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Osthole activates glucose uptake but blocks full activation in L929 fibroblast cells, and inhibits uptake in HCLE cells

AIMS: Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines that exclusively express GLUT1. MAIN METH...

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Publicat a:Life Sci
Autors principals: Alabi, Ola D., Gunnink, Stephen M., Kuiper, Benjamin D., Kerk, Samuel A., Braun, Emily, Louters, Larry L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001691/
https://ncbi.nlm.nih.gov/pubmed/24657891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2014.03.017
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