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Osthole activates glucose uptake but blocks full activation in L929 fibroblast cells, and inhibits uptake in HCLE cells

AIMS: Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines that exclusively express GLUT1. MAIN METH...

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Detalhes bibliográficos
Publicado no:Life Sci
Main Authors: Alabi, Ola D., Gunnink, Stephen M., Kuiper, Benjamin D., Kerk, Samuel A., Braun, Emily, Louters, Larry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001691/
https://ncbi.nlm.nih.gov/pubmed/24657891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2014.03.017
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