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Bromodeoxyuridine does not contribute to sister chromatid exchange events in normal or Bloom syndrome cells

Sister chromatid exchanges (SCEs) are considered sensitive indicators of genome instability. Detection of SCEs typically requires cells to incorporate bromodeoxyuridine (BrdU) during two rounds of DNA synthesis. Previous studies have suggested that SCEs are induced by DNA replication over BrdU-subst...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: van Wietmarschen, Niek, Lansdorp, Peter M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001594/
https://ncbi.nlm.nih.gov/pubmed/27185886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw422
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