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Bromodeoxyuridine does not contribute to sister chromatid exchange events in normal or Bloom syndrome cells

Sister chromatid exchanges (SCEs) are considered sensitive indicators of genome instability. Detection of SCEs typically requires cells to incorporate bromodeoxyuridine (BrdU) during two rounds of DNA synthesis. Previous studies have suggested that SCEs are induced by DNA replication over BrdU-subst...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: van Wietmarschen, Niek, Lansdorp, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001594/
https://ncbi.nlm.nih.gov/pubmed/27185886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw422
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