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Bromodeoxyuridine does not contribute to sister chromatid exchange events in normal or Bloom syndrome cells

Sister chromatid exchanges (SCEs) are considered sensitive indicators of genome instability. Detection of SCEs typically requires cells to incorporate bromodeoxyuridine (BrdU) during two rounds of DNA synthesis. Previous studies have suggested that SCEs are induced by DNA replication over BrdU-subst...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: van Wietmarschen, Niek, Lansdorp, Peter M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001594/
https://ncbi.nlm.nih.gov/pubmed/27185886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw422
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