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Bromodeoxyuridine does not contribute to sister chromatid exchange events in normal or Bloom syndrome cells
Sister chromatid exchanges (SCEs) are considered sensitive indicators of genome instability. Detection of SCEs typically requires cells to incorporate bromodeoxyuridine (BrdU) during two rounds of DNA synthesis. Previous studies have suggested that SCEs are induced by DNA replication over BrdU-subst...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001594/ https://ncbi.nlm.nih.gov/pubmed/27185886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw422 |
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