Single base resolution analysis of 5-hydroxymethylcytosine in 188 human genes: implications for hepatic gene expression

To improve the epigenomic analysis of tissues rich in 5-hydroxymethylcytosine (hmC), we developed a novel protocol called TAB-Methyl-SEQ, which allows for single base resolution profiling of both hmC and 5-methylcytosine by targeted next-generation sequencing. TAB-Methyl-SEQ data were extensively va...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ivanov, Maxim, Kals, Mart, Lauschke, Volker, Barragan, Isabel, Ewels, Philip, Käller, Max, Axelsson, Tomas, Lehtiö, Janne, Milani, Lili, Ingelman-Sundberg, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001587/
https://ncbi.nlm.nih.gov/pubmed/27131363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw316
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