MicroRNA-181b inhibits thrombin-mediated endothelial activation and arterial thrombosis by targeting caspase recruitment domain family member 10

Thrombogenic and inflammatory mediators, such as thrombin, induce NF-κB–mediated endothelial cell (EC) activation and dysfunction, which contribute to pathogenesis of arterial thrombosis. The role of anti-inflammatory microRNA-181b (miR-181b) on thrombosis remains unknown. Our previous study demonst...

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Detalles Bibliográficos
Publicado en:FASEB J
Autores principales: Lin, Jibin, He, Shaolin, Sun, Xinghui, Franck, Gregory, Deng, Yihuan, Yang, Dafeng, Haemmig, Stefan, Wara, A. K. M., Icli, Basak, Li, Dazhu, Feinberg, Mark W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001512/
https://ncbi.nlm.nih.gov/pubmed/27297585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500163R
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