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Biochemical and structural analysis of the interaction between β-amyloid and fibrinogen
The majority of patients with Alzheimer disease (AD) suffer from impaired cerebral circulation. Accumulating evidence suggests that fibrinogen, the main protein component of blood clots, plays an important role in this circulatory dysfunction in AD. Fibrinogen interacts with β-amyloid (Aβ), forming...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5000847/ https://ncbi.nlm.nih.gov/pubmed/27389717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-705228 |
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