Cytoprotection against Hypoxic and/or MPP(+) Injury: Effect of δ–Opioid Receptor Activation on Caspase 3

The pathological changes of Parkinson’s disease (PD) are, at least partially, associated with the dysregulation of PTEN-induced putative kinase 1 (PINK1) and caspase 3. Since hypoxic and neurotoxic insults are underlying causes of PD, and since δ-opioid receptor (DOR) is neuroprotective against hypo...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Xu, Yuan, Zhi, Feng, Shao, Naiyuan, Wang, Rong, Yang, Yilin, Xia, Ying
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000589/
https://ncbi.nlm.nih.gov/pubmed/27517901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081179
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