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Modulation of Acid-sensing Ion Channel 1a by Intracellular pH and Its Role in Ischemic Stroke
An important contributor to brain ischemia is known to be extracellular acidosis, which activates acid-sensing ion channels (ASICs), a family of proton-gated sodium channels. Lines of evidence suggest that targeting ASICs may lead to novel therapeutic strategies for stroke. Investigations of the rol...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5000083/ https://ncbi.nlm.nih.gov/pubmed/27402850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.713636 |
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