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The pharmacology and therapeutic potential of small molecule inhibitors of acid-sensing ion channels in stroke intervention
In the nervous system, a decrease in extracellular pH is a common feature of various physiological and pathological processes, including synaptic transmission, cerebral ischemia, epilepsy, brain trauma, and tissue inflammation. Acid-sensing ion channels (ASICs) are proton-gated cation channels that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616483/ https://ncbi.nlm.nih.gov/pubmed/22820909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.81 |
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