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Inhibition of HDAC6 Protein Enhances Bortezomib-induced Apoptosis in Head and Neck Squamous Cell Carcinoma (HNSCC) by Reducing Autophagy

Chemoresistance is a major barrier to effective chemotherapy of solid tumors, including head and neck squamous cell carcinoma (HNSCC). Recently, autophagy, a highly conservative intracellular recycling system, has shown to be associated with chemoresistance in cancer cells. However, little is known...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chang, Insoon, Wang, Cun-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000068/
https://ncbi.nlm.nih.gov/pubmed/27369083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.717793
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