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Bortezomib Induces Autophagy in Head and Neck Squamous Cell Carcinoma Cells via JNK Activation

The molecular mechanism of autophagy induction following proteasome inhibition is not fully understood. We report that the proteasome inhibitor bortezomib potently induces autophagy in head and neck squamous cell carcinoma (HNSCC) cells, as demonstrated by autophagosome formation and induction of co...

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Autori principali: Li, Changyou, Johnson, Daniel E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225600/
https://ncbi.nlm.nih.gov/pubmed/21993018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.09.020
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