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Bortezomib Induces Autophagy in Head and Neck Squamous Cell Carcinoma Cells via JNK Activation
The molecular mechanism of autophagy induction following proteasome inhibition is not fully understood. We report that the proteasome inhibitor bortezomib potently induces autophagy in head and neck squamous cell carcinoma (HNSCC) cells, as demonstrated by autophagosome formation and induction of co...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3225600/ https://ncbi.nlm.nih.gov/pubmed/21993018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.09.020 |
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